This roundtable will explore how companies are transforming their data centers in the face of the impact of artificial intelligence - from high energy density to operational management - and how the integration of hybrid and private cloud models is redefining architecture and operations. A real case of High Performance Computing (HPC) for AI loads applied to medical imaging will be analyzed, and it will be shown how an intelligent platform based on AI and machine learning can optimize the use of resources and the performance of both facilities and IT infrastructure.